Spectrophotometric determination of drugs using

نویسندگان

  • Arshiya Fathima
  • Kanakapura Basavaiah
چکیده

Seven drugs viz., Paroxetine, Famotidine, Quetiapine, Dextromethorphan, Levofloaxacin, Irbesartan and Itraconazole were tested for the formation of charge transfer complexes with DDQ and the interaction formed a basis for spectrophotometric determination of the drugs. Acetonitrile was found to be suitable solvent for the analysis. The methods have been validated in terms of ICH guidelines The complexes were found to have 1:1 composition and have stability of the order 10 3 to 10 4

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تاریخ انتشار 2011